CURRICULUM VITAE
姓名Name:
謝孟樵 Meng-Chiao Hsieh
性別Sex:
男性Male
電子信箱 E-mail:
職稱Affiliation:
嘉義長庚紀念醫院大腸直腸肛門外科 助理教授級主治醫師
Assistant Professor of Division of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital Chiayi Branch, Chiayi, Taiwan
辦公室地址Office Address:
61363 嘉義縣朴子市嘉朴路西段6號 嘉義長庚紀念醫院
No 6, Sec West, Chia-Pu Rd, Puzih, Chiayi County 61363, Taiwan
學經歷Academic Appointment:
1999年9月至2005年6月 Sep. 1999-Jun. 2005
台北醫學大學醫學系
Medicine, Taipei Medical University, Taipei, Taiwan.
2005年6月至2006年5月 Jun. 2005-Mar.2006
台北醫學大學附設醫院及台北市立萬芳醫院實習醫學生
Internship, Taipei Medical University Hospital and Wan Fang Hospital.
2006年8月至2008年7月 Aug. 2006-Jul. 2008
林口長庚紀念醫院外科住院醫師
嘉義長庚紀念醫院外科住院醫師
Residency of Surgery, Chang Gung Memorial Hospital Linko Branch, Taoyuan, Taiwan
Residency of Surgery, Chang Gung Memorial Hospital Chiayi Branch, Chiayi, Taiwan
2008年8月至2012年7月 Aug. 2008-Jul. 2012
嘉義長庚紀念醫院大腸直腸肛門外科 總住院醫師
Chief Resident of Colorectal Surgery, Chang Gung Memorial Hospital Chiayi Branch, Chiayi, Taiwan
2012年8月至2016年6月 Aug. 2012-Jun. 2016
嘉義長庚紀念醫院大腸直腸肛門外科 一般級主治醫師
Attending Physician of Colorectal Surgery, Chang Gung Memorial Hospital Chiayi Branch, Chiayi, Taiwan
2012年12月至2013年1月 Dec. 2012-Jan. 2013
日本國立癌症研究中心中央醫院 內視鏡科 短期臨床研究員
Clinical Fellowships, Department of Endoscopy, Gastrointestinal Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
2016年7月至今 Jul. 2016-Now
嘉義長庚紀念醫院大腸直腸肛門外科 助理教授級主治醫師
Assistant Professor of Division of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital Chiayi Branch, Chiayi, Taiwan
執業執照Professional Affiliations:
Taiwan Medical Association:Board No.: 039907
Taiwan Surgery Association :Board No.: 006136
Society of Colon and Rectal Surgeon, Taiwan:Board No.: 329
Taiwan Society of Critical Care Medicine:Board No.: 02738
Advanced Trauma Life Support® Student Course:Board No.: 1010714
獲獎獎項Awards
2014.7
第15屆實證醫學文獻查證競賽臨床組銀獎
Silver Medal, 15th Health Quality Improvement Competition (HQIC) Evidence-based Medicine Clinical Group
2015.6
第16屆實證醫學文獻查證競賽臨床組銅獎
Bronze Medal, 16th Health Quality Improvement Competition (HQIC) Evidence-based Medicine Elite Group
1. Chen CH, Hsieh MC, Lai CC, Yeh YC, Chen
JS, Hsieh PS, Chiang JM, Tsai WS, Tang RP, Cangchien CR, Wang JY Lead time of carcinoembryonic antigen
elevation in the postoperative follow-up of colorectal cancer did not affect
the survival rate after recurrence Int
J Colorectal Dis 2010 ;25(5):567-71. DOI:
10.1007/s00384-010-0889-6. 2015 IF: 2.449
2. Hsieh MC, Chin CC, Huang WS, Yeh
CH, Kuo YH, Chen JS, Wang JY Risk Factors and Postoperative Morbidities in
Colon Cancer Patients with Preoperative Hypoalbuminemia J Soc Colon Rectal Surgeon (Taiwan) 2012;23:6-12. DOI:
10.6312/SCRSTW.2012.23(1).10012.
3. Huang CY, Chin CC,
Hsieh MC, Kuo YH, Huang WS,
Yeh CH, Chen JS, Tang RP, Wang JY. The Relationship between the Presentation of
Hematochezia and Colon Cancer. J Soc
Colon Rectal Surgeon (Taiwan) 2012;23:160-167. DOI:
10.6312/SCRSTW.2012.23(4).10113.
4. Hsieh MC*, Peng KT*,
Hsu WH, Li YY, Yeh CH Anterior ilioinguinal incision for drainage of
high-located perianal abscess. Tech
Coloproctol 2013;17:455-458. DOI:
10.1007/s10151-012-0902-x. *Co-first
author. 2015 IF: 2.320
5. Shen CH, Tung SY, Huang WS, Lu CC, Lee KC, Hsieh YY, Chang PJ, Liang HF, Chen JH, Lin TH, Hsieh
MC, Kuo HC.
Exploring the effects of tert-butylhydroperoxide induced liver injury using
proteomic approach. Toxicology. 2014;316:61-70.
DOI: 10.1016/j.tox.2013.12.007. 2015 IF:
3.817
6. Hsieh YY, Shen CH,
Huang WS, Chin CC, Kuo YH, Hsieh MC,
Yu HR, Chang TS, Lin TH, Chiu YW, Chen CN, Kuo HC, Tung SY. Resistin-induced stromal cell-derived factor-1 expression through
Toll-like receptor 4 and activation of p38 MAPK/ NFκB signaling pathway in
gastric cancer cells. J Biomed Sci.
2014;21:59. DOI: 10.1186/1423-0127-21-59. 2015
IF: 2.935
7. Lee KF, Chen JH,
Teng CC, Shen CH, Hsieh MC, Lu
CC, Lee KC, Lee LY, Chen WP, Chen CC, Huang WS, Kuo HC. Protective effects of Hericium erinaceus mycelium and its isolated
erinacine A against ischemia-injury-induced neuronal cell death via the inhibition
of iNOS/p38 MAPK and nitrotyrosine. Int J Mol Sci. 2014;15:15073-15089. DOI: 10.3390/ijms150915073. 2015 IF: 3.257
8. Chin CC, Chen CN,
Kuo HC, Shi CS, Hsieh MC, Kuo
YH, Tung SY, Lee KF, Huang WS. Interleukin-17
induces CC chemokine receptor 6 expression and cell migration in colorectal
cancer cells.
J Cell Physiol. 2015;230:1430-1437.
DOI: 10.1002/jcp.24796. 2015 IF: 4.155
9. Hsieh MC, Kuo LT,
Chi CC, Huang WS, Chin CC. Pursestring Closure versus Conventional Primary
Closure Following Stoma Reversal to Reduce Surgical Site Infection Rate: A
Meta-analysis of Randomized Controlled Trials. Dis Colon Rectum. 2015;58: 808-815. DOI:
10.1097/DCR.0000000000000401. 2014 IF: 3.749
10. Hou CP, Lin YH, Hsieh MC, Chen CL, Chang PL,
Huang YC, Tsui KH. Identifying the variables associated with pain during
transrectal ultrasonography of the prostate. Patient Prefer Adherence. 2015;9:1207–1212. DOI:
10.2147/PPA.S83073. 2015 IF: 1.718
11. Hsieh MC, Chen CJ, Huang WS. McKittrick-Wheelock
Syndrome. Clin Gastroenterol Hepatol. 2016;14:e41–e42.
DOI: 10.1016/j.cgh.2015.09.001. 2015 IF:
7.896
12. Kuo HC, Lu CC,
Shen CH, Tung SY, Hsieh MC,
Lee KC, Lee LY, Chen CC, Teng CC, Huang WS, Chen TC, Lee KF. Hericium erinaceus
mycelium and its isolated erinacine A protection from MPTP-induced
neurotoxicity through the ER stress, triggering an apoptosis cascade. J Transl
Med. 2016;14:78. DOI: 10.1186/s12967-016-0831-y. 2015 IF: 3.93
13. Lu CC, Huang WS,
Lee KF, Lee KC, Hsieh MC,
Huang CY, Lee LY, Lee BO, Teng CC, Shen CH, Tung SY, Kuo HC. Inhibitory effect
of Erinacines A on the growth of DLD-1 colorectal cancer cells is induced by
generation of reactive oxygen species and activation of p70S6K and p21. J Funct Foods. 2016;21:474-484. 2015 IF: 3.574
14. Hsieh MC, Huang WS, Chin CC, Kuo
YH, Peng KT. Drainage of a complicated high perianal abscess: a bilateral
ilioinguinal approach. Tech Coloproctol. 2016;
20:595-596. DOI: 10.1007/s10151-016-1480-0.
2015 IF: 2.320
15. Yeh CY, Jao SW,
Chen JS, Fan CW, Chen HH, Hsieh PS, Wu CC, Lee CC, Kuo YH, Hsieh MC, Huang WS, Chung YC, Liou TY, Chiu HH, Tseng WK,
Lee KC, Wang JY. Sebacoyl Dinalbuphine Ester Extended-release Injection for
Long-acting Analgesia: A Multicenter, Randomized, Double Blind, and Placebo-controlled
Study in Hemorrhoidectomy Patients. J
Clin Pain. 2017; 33: 429-434.
DOI: 10.1097/AJP.0000000000000417
2015 IF: 2.703
16. Hsieh MC*, Huang WS*, Huang CY, Kuo YH, Tung SY,
Shen CH, Hsieh YY, Teng CC, Lee KF, Chen TC, Lee KC, Kuo HC. The Association of CXC Receptor 4 mediated signaling
pathway with oxaliplatin-resistant human colorectal cancer cells. PLoS ONE. 2016; 11(9): e0159927. *Co-first
author DOI:
10.1371/journal.pone.0159927 2015 IF: 3.057
17. Lee
KC, Kuo HC2, Shen CH, Lu CC, Huang WS, Hsieh
MC, Huang CY, Kuo YH, Hsieh YY, Teng CC, Lee LY, Tung SY. A proteomics approach to
identifying novel protein targets involved in erinacine A mediated inhibition
of colorectal cancer cells' aggressiveness. J
Cell Mol Med. 2017; 21:588-599. DOI: 10.1111/jcmm.13004. 2015 IF: 4.938
18. Kuan FC, Lai CH,
Ku HY, Wu CF, Hsieh MC, Liu TW, Yeh CY, Lee KD. The
survival impact of delayed surgery and adjuvant chemotherapy on stage II/III
rectal cancer with pathological complete response after neoadjuvant
chemoradiation. Int J Cancer. 2017; 140:1662-1669. DOI: 10.1002/ijc.30562. 2015 IF: 5.531
19. Huang WS, Kuo YH,
Kuo HC, Hsieh MC, Huang CY,
Lee KC, Lee KF, Shen CH, Tung SY, Teng CC. CIL-102-Induced Cell Cycle Arrest
and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45. PLoS One. 2017; 12(1): e0168989. DOI:
10.1371/journal.pone.0168989. 2015 IF:
3.057
20. Kuo YH, Huang CY,
Chen CJ, Hsu CH, Chuang HC, Lee TH, Hsieh
MC, Huang WS, Chien CC. Impact of KRAS mutation on second-line
oxaliplatin-based (FOLFOX-6) chemotherapy for metastatic colorectal cancer. J Soc Colon Rectal Surgeon (Taiwan) 2017;
28:34-42. DOI: 10.6312/SCRSTW.2017.28(1).10530
21. Wang TY, Chen CY,
Lu CH, Chen MC, Lee LW, Hsieh MC,
Chen CJ, Yu CM, Chuang HC, Liao TT, Tseng CW, Huang WS. Cytoreductive Surgery
with Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Malignancy:
Preliminary Results of a Multi-Disciplinary Teamwork Model in Asia. Int J Hyperthermia. 2017; 23: 1-8 DOI: 10.1080/02656736.2017.1337238 2015 IF: 3.361
22. Kuo HC, Kuo YR, Lee KF, Hsieh MC, Huang CY, Hsieh YY, Lee KC, Kuo HL, Lee LY, Chen WP, Chen CC, Tung SY. A Comparative Proteomic Analysis of Erinacine A's Inhibition of Gastric Cancer Cell Viability and Invasiveness. Cell Physiol Biochem. 2017; 43: 195-208. DOI: 10.1159/000480338. 2015 IF: 5.104
23. Hsieh MC, Wu CF, Chen CW, Shi CS, Huang WS, Kuan FC. Hypomagnesemia
and clinical benefits of anti-EGFR monoclonal antibodies in wild-type KRAS
metastatic colorectal cancer: a systematic review and meta-analysis. Sci Rep. 2018 Feb 1; 8: 2047. DOI: 10.1038/s41598-018-19835-8. 2016 IF: 4.259
24. Shen CH, Tung SY, Huang WS, Lee KF, Hsieh YY, Hsieh MC, Chen CN, Kuo HC. Comparative Proteomic Identification of Protein Disulphide Isomerase A6 Associated with Tert-Butylhydroperoxide-Induced Liver Injury in Rat Hepatocytes. Cell Physiol Biochem. 2018; 45: 1915-1926. DOI: 10.1159/000487968. 2016 IF: 5.5
25. Huang WS, Huang CY, Hsieh MC, Tung SY, Shen CH, Hsieh YY, Tenge CC, Lee KC, Lee KF, Kuo HC. Expression of PRDX6 Correlates with Migration and Invasiveness of Colorectal Cancer Cells. Cell Physiol Biochem. 2018;51: 2616-2630. DOI: 10.1159/000495934.
26. Sun CY, Hsieh
MC, Kuo LM, Chen CH, Huang YI, Huang WS. Single-incision Laparoscopic
Surgery Using a Transumbilical Glove-port for Synchronous Colectomy and
Hepatectomy: A Preliminary Experience in 9 Patients. J Soc Colon Rectal
Surgeon (Taiwan). 2019;30; 36-44. DOI: 10.6312/SCRSTW.201903_30(1).10715
27. Lee KY, Lee
KF, Tung SY, Huang WS, Lee LY, Chen WP, Chen CC, Teng CC, Shen CH, Hsieh
MC, Kuo HC. Induction Apoptosis of Erinacine A in Human Colorectal
Cancer Cells Involving the Expression of TNFR, Fas, and Fas Ligand via the
JNK/p300/p50 Signaling Pathway With Histone Acetylation. Front Pharmacol.
2019, Oct 1x; 10: 117x DOI: 10.3389/fphar.2019.01174
28. Lee KF,
Tung SY, Teng CC, Shen CH, Hsieh MC, Huang CY, Lee KC, Lee LY,
Chen WP, Chen CC, Huang WS, Kuo HC. Post-Treatment with Erinacine A, a Derived
Diterpenoid of H. erinaceus, Attenuates Neurotoxicity in MPTP Model of
Parkinson’s Disease. Antioxidants. 2020;9:137. DOI:10.3390/antiox9020137
29. Hsieh
MC, Lai CH, Kuo YH, Chin
CC, Huang WS. Neoadjuvant Short-Course Radiotherapy or Concurrent
Chemoradiotherapy Followed by Radical Colectomy in Locally Advanced Colon
Cancer Patients. J Soc Colon Rectal Surgeon (Taiwan). 2020;31:123-133.
DOI:10.6312/SCRSTW.202009_31(3).10833
30. Hsieh
MC, Lee TH, Huang WS. Chronic
Nonhealing Colonic Ulcer. Clin Gastroenterol Hepatol. 2020 Jun
1:S1542-3565(20)30757-6. DOI: 10.1016/j.cgh.2020.05.050. Epub ahead of print.